Another research [51] showed that drug-resistant osteosarcoma cell line KHOSR2 and virally-derived osteoblast cell line hFOB had high (3-log) PD-L1 gene expression, and osteosarcoma cell line SaOS and breast cancer cell line MCF-7 had low (< 1-log) expression. The gene discussed is CD274; the disease is breast carcinoma.