Endothelial cells (ECs) isolated from the bone marrow of multiple myeloma patients (MMECs) express EC markers, including Tie2, vascular endothelial growth factor receptor-2 (VEGFR-2), fibroblast growth factor receptor-2 (FGFR-2), CD105-endoglin and vascular endothelial (VE)-cadherin. The gene discussed is KDR; the disease is plasma cell myeloma.