AKT1 and metastatic colorectal cancer: Additional miR-30a–regulated targets have been identified and their functions defined, including involvement in tumor cell autophagy [28], mediating cis-platinum chemosensitivity [29], suppressing metastatic colorectal cancer by inactivating the Akt/mTOR pathway [30], and inhibiting breast cancer metastasis by decreasing metadherin [31].