GPX3 and Hypoglycemia: Interestingly, we previously showed that GSH metabolism is decreased during hypoglycemia, with both an increase of the glutathione peroxidase 3 (Gpx3) and the glutathione S-transferase omega 1 (Gsto-1) expression either in vivo during single hypoglycemia, and in 661W photoreceptor cells or in C57BL/6 isolated retina cultured at low glucose concentration [3].