To further validate the in vivo significance of MALAT1 on tumor growth in vivo, we used a xenograft model in which the MCF-7 cells treated with MALAT1-siRNA (5/mice), miR-124 inhibitor (5/mice), miR-124 inhibitor+MALAT1-siRNA (5/mice) and PBS as control (3/mice) were subcutaneously injected into nude mice. Here, MALAT1 is linked to neoplasm.