Transcriptional profiling using Affymetrix GeneChip human genome arrays was performed in two K-ras dependent (H2009 and H441) and two K-ras independent (A549 and H460) NSCLC cell lines that stably express shRNA targeting either the coding region of PKCδ (δ193) or a scrambled non-targeting sequence (δscr). The gene discussed is KRAS; the disease is non-small cell lung carcinoma.