IFNAR1 and infection: It should be noted that although there was perturbation of a larger number of transcripts at days 2 and 3 as a result of infection, in blood and tissues of both Ifnar1-/- and WT mice, unique transcripts were also perturbed at each of the different time points post-infection in Ifnar1-/- and WT mice, with some differentially expressed common transcripts observed between time points (Fig 3D).