IFNAR1 and infection: An increase in the proportion of Ly6C+ monocytes was observed in the blood of WT mice upon infection but not in the blood of Ifnar1-/- infected mice at day 3 post infection (Fig 6B, S4 Fig), in keeping with the observations that antigen presentation pathway at the transcriptional level was elevated in the blood of infected WT as compared to infected Ifnar1-/- mice (Fig 4C).