CXCL10 and neoplasm: Analysis of immune mediator expression in Pan02 tumours at day 29 revealed that αCD40 significantly upregulated the Th1 chemokine CXCL10 at the mRNA (Figure 2E) and protein (Figure 2F) level in Pan02 tumours, along with IL-2 (Figure 2E, 2G), perhaps explaining the expansion or increased infiltration of tumour CD8+ T cells.