These CTHRC1-knockdown cells showed an even larger decrease in the mRNA levels of CTHRC1 and the other downregulated genes compared to those of the control shRNA cells (Supplementary Table S7) To further evaluate the generality of these findings, we analyzed the expression levels of these potential downstream targets of CTHRC1 in another melanoma cell line, MM170, with similar results (Supplementary Table S7). This evidence concerns the gene CTHRC1 and melanoma.