The effector function of T cells to control virus replication and eliminate the infection is directed through the production of cytokines, including IFN-γ, or direct killing of infected cells through secretion of perforin and signaling through Fas to -Fas ligand, or TNF-related apoptosis-inducing ligand (TRAIL)-dependent pathways68,102,103. Here, TNFSF10 is linked to infection.