CCDC88Aencodes the actin binding protein girdin, which has previously been demonstrated as a binding partner of Akt and to play essential roles in the migration of fibroblasts, endothelial cells, cancer cells and neuronal cells (Enomotoet al., 2005,2009;Jianget al., 2008;Kitamuraet al., 2008). This evidence concerns the gene AKT1 and cancer.