Furthermore, our comparative analysis of the expression levels of KDM5B in 23 paired breast carcinoma and adjacent non-neoplastic tissues from TMU-SHH breast cancer patients’ cohort using western blot showed that the expression levels of KDM5B were elevated in 21 of 23 cases of breast cancer specimens compared with those of adjacent non-neoplastic tissues (p < 0.001) (Fig. 1d & e). Here, KDM5B is linked to breast cancer.