We probed the TCGA illuminaHiSeq breast invasive carcinoma dataset consisting of 1182 human breast tumor cases, and demonstrated notable similarity in gene expression levels and proportion in the probed samples (Fig. 6a & b), while our qRT-PCR demonstrated that downregulation of KDM5B expression via shRNA induced a significant concomitant suppression of MALAT 1 expression (Fig. 6c–e). The gene discussed is KDM5B; the disease is invasive breast carcinoma.