RETN and Hypertension: Both systolic BP (SBP) and diastolic BP (DBP) were markedly higher in WT mice treated with resistin for 6 days [Fig. 1B, SBP: 104 ± 6 (Retn, D0), 140 ± 20 (Retn, D6) mmHg; DBP: 67 ± 12 (Retn, D0), 87 ± 15 (Retn, D6) mmHg], whereas no differences were observed in WT mice treated with PBS [Fig. 1B, SBP: 103 ± 6 (Con, D0), 101 ± 13 (Con, D6) mmHg; DBP: 69 ± 11 (Con, D0), 66 ± 8 (Con, D6) mmHg], indicating that resistin caused hypertension in WT mice.