Mutation screening of PLN in 315 patients with cardiomyopathy (ARVC (n = 111)14, DCM (n = 95)15, HCM (n = 40)16, and peripartum cardiomyopathy (PPCM) (n = 69))17 revealed the previously reported c.25C > T (p.R9C) mutation in a proband of European descent with severe DCM (DCM 320.1; Individual II:2)6. The gene discussed is PLN; the disease is arrhythmogenic right ventricular cardiomyopathy.