MMP14 and neoplasm: The number of MT1-MMP-transfected cells that traversed the pored filters was 317.33 ± 6.43, compared with 225.67 ± 22.37 for the control cells (P < 0.05, Fig. 4), indicating that Eca109 cells overexpressing MT1-MMP are more invasive than empty-vector-transfected tumor cells.