Fig 3 shows the relationships between the absolute course of change in inflammatory mediators and cf-PWV We found statistically significant inverse associations between increases in the absolute course of change in CC-16 concentrations and the absolute course of change in cf-PWV over time (Fig 3A) as well as between increases in the absolute course of change in RelB concentrations and the absolute course of change in cf-PWV over time (Fig 3C). There was a trend for an inverse association between SPD and cf-PWV over time (Fig 3B). Here, RELB is linked to Platelet storage pool disease.