MRPL58 and Alzheimer disease: This particular SNP, rs9899728, showed a larger effect on SVD (OR [95% confidence interval {CI}] = 1.32 (1.14–1.52); p = 0.00014) than AD (OR [95% CI] = 1.20 [1.11–1.30]; p = 7.1 × 10−6) and falls between two genes: Immature Colon Carcinoma Transcript 1 (ICT1) and adenosine triphosphate (ATP) synthase, H + transporting, mitochondrial Fo complex, subunit (ATP5H).