ADGRE1 and neoplasm: In contrast, other major cell type markers, such as Villin (VIL1, enterocytes), DLL1 (progenitor cells), F4/80 (EMR1, macrophages), Gr-1 (LY6G5B, leukocytes), or β-catenin (CTNNB, colon epithelia), did not show such strong suppression (Figure 3—figure supplement 1A–E), while the stem cell marker LGR5 was rather upregulated in tumor samples (Figure 3—figure supplement 1A–E).