PAX7 and Cachexia: Further, cKO animals with cachexia had an ~2-fold increase in the percentage of TUNEL+/Pax7+ cells compared with WT tumor-bearing animals, indicating that the smaller Pax7+ population found in cKO animals is also mostly apoptotic and suggesting that C/EBPβ may acts to protect SCs from apoptosis in the context of chronic inflammation typical of cachexia (Figures 5h and i).