In > 18‐month‐old VEGF‐Ahyper mice, about 59% of these mice had formed mature (grade 3) cataracts with complete opacification and leukocoria, while only about 12% of wild‐type mice in this age group formed mature cataracts (Fig 4A and Appendix Fig S1). The gene discussed is VEGFA; the disease is cataract.