NLRP3 and age-related macular degeneration: In preliminary experiments with 6‐week‐ to 2‐month‐old VEGF‐Ahyper mice that lacked either Nlrp3, Il1r1, or Il18, we had previously observed the occasional occurrence of some VEGF‐A‐induced chorioretinal pathologies, but we had not performed a detailed analysis of the age‐dependent AMD‐like pathologies in these mice with progressive age (Marneros, 2013).