VEGFA and blindness (disorder): Importantly, VEGF‐Ahyper mice developed in an age‐dependent progressive manner cataracts whose age‐related onset and increase in severity resembled aspects of human age‐related cataracts (Fig 3B–G), which represent the most frequent form of cataracts and the most common cause of reversible blindness (Rao et al, 2011; Petrash, 2013).