We observed in eyes of all VEGF‐Ahyper mice examined (> 400 mice were examined in total, between ages 6 weeks to 34 months) an age‐dependent manifestation of AMD‐like pathologies with CNV and progressive RPE/photoreceptor degeneration (Fig 5, Appendix Figs S2 and S3) (Marneros, 2013; Ablonczy et al, 2014). The gene discussed is VEGFA; the disease is age-related macular degeneration.