All MDA-MB-468 tumours were detected reliably by in vivo SPECT scans 45 min after administration of 17 pmol anti-EGFR nanobody 99mTc-D10 as shown by signals present in the tumour and very low background signals resulting in a tumour to tissue (area of the contra lateral side) ratio of 42.8 ± 27.0 (Fig. 5d, Table 2). The gene discussed is EGFR; the disease is neoplasm.