After initial hemostasis success using EVL, rebleeding-free survival was predicted by the presence of a PVTT in the main trunk influencing portal vein pressure, and overall survival was predicted by Child-Pugh class and AFP-L3 levels, which are not directly related to variceal severity, but rather reflect liver function and the malignant potential of the HCC a determinant of prognosis. Here, AFP is linked to hepatocellular carcinoma.