After adjusting for age and reproductive risk factors, subjects carrying G allele of rs12443621 in TNRC9 were found to have a higher breast cancer risk compared with those carrying AA genotype (AG vs AA: OR = 0.621, 95 % CI = 0.075–5.129; GG vs AA: OR = 1.569, 95 % CI = 0.233–10.556). Here, TOX3 is linked to breast cancer.