Increases in ocular Ccl- and Cxcl- chemokines are also found in individuals affected by retinal detachment [62, 63], uveitis [64], glaucoma [65], diabetic retinopathy, and retinitis pigmentosa [66], while blockade of Ccl2 signalling has proven beneficial in thwarting macrophage aggregation and cell death in experimental retinal detachment, diabetic retinopathy [23], and retinitis pigmentosa [67]. This evidence concerns the gene CCL2 and retinitis pigmentosa.