CEACAM1 and myocardial infarction: Eight weeks after MI, the terminal deoxynucleotidyl-transferase–mediated dUTP nick-end labeling (TUNEL) assay showed significantly more apoptotic cells (red) in the non-infarct area in the MI groups than in the corresponding sham groups (P < 0.01, Fig. 4A,B), while the number of apoptotic cells was much lower in CEACAM1 KO-MI mice than in WT-MI mice (P < 0.01, Fig. 4A,B), indicating that deletion of CEACAM1 reduced apoptosis after MI.