Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1, also termed CD66a) is a transmembrane protein that has been recognized as an important tumor-associated factor which suppresses or promotes carcinogenesis in a context-dependent manner13, 14, but it remains unknown whether CEACAM1 has any role like p53 in cardiovascular disease. Here, CEACAM1 is linked to cardiovascular disorder.