TP53 and neoplasm: Because some circulating tumor-associated factors such as p53 are potential diagnostic and prognostic biomarkers for MI30 and HF31, we measured the serum level of CEACAM1 in MI patients and healthy controls, revealing that serum CEACAM1 was significantly higher in the MI patients than in the controls (5760 ± 289 pg/mL vs. 4444 ± 350 pg/mL, P < 0.01) (Fig. 1).