Among them, interferon (IFN) inducible CXC chemokine, CXCL9 (Mig), CXCL10 (IP-10) and CXCL11 (I-TAC), are multifunctional chemokine orchestrating immunity and angiogenesis via shared G-protein coupled receptor CXCR3, thus, these ligands might play a crucial role in cancer [6, 7]. The gene discussed is CXCL11; the disease is cancer.