We next divided human breast tumor samples into three groups: IMP1 negative (n = 15), IMP1 weakly expressed (such as numbers 33 and 39 in Figure 7C, n = 11) and IMP1 highly expressed group (such as numbers 36 and 40 in Figure 7C, n = 21), and examined correlations between IMP1 expression and levels of PTGS2, GDF15 and IGF-2 mRNAs. The gene discussed is GDF15; the disease is breast neoplasm.