Also, our lab previously reported that SLC34A2 was down-regulated in human NSCLC tumor tissues and cells, and might act as tumor suppressor by inhibiting the growth, invasion and migration of lung cancer cells through the PI3K-Akt-mTOR and Ras-Raf-MEK-ERK signaling pathway [16, 17]. The gene discussed is SLC34A2; the disease is lung cancer.