In the low grade intraepithelial neoplasias with mutant KRAS, 46(46/123,37.4%)were tubulovillous adenomas, 24(24/155,15.5%) were tubular adenomas, 12(12/52,23.1%)were serrated adenomas, and 3(3/7,42.9%) were villous adenomas (Table 2). This evidence concerns the gene KRAS and tubular adenoma.