Additionally CD24 expression has been reported in discs from children and adolescents undergoing surgery for scoliosis.23 Furthermore, a subpopulation of CD24 positive mouse embryoid body cells showed spontaneous differentiation to cells with notochordal characteristics.39 Collectively, these findings have led to the proposal of CD24 as a healthy NP marker40 which may depict a cell of notochordal origin. Here, CD24 is linked to scoliosis.