This is probably due to the fact that the OGTT is typically ordered for gestational diabetes screening between week 24–28 of gestation, a period within which insulin resistance in already present as a result of the increased production of placental lactogen, in addition to the higher concentrations of cortisol, estrogen, progesterone and prolactin, which also decrease the sensitivity to insulin (23). The gene discussed is PRL; the disease is Insulin resistance.