MYC and prostate intraepithelial neoplasia: Prostatic epithelial expression of c-Myc in the dorsolateral prostate (DLP), ventral prostate (VP), and anterior prostate (AP) lobes results in complete penetrance of prostatic intraepithelial neoplasia (PIN) as early as 2 to 4 weeks of age, which progress to locally invasive adenocarcinomas within 6 to 12 months of age [23, 24].