To summarize, an increased percentage of CD8+ T cells was seen in the dLN of Nox1*/Y after PR8 infection, with increased CD8+ T cells in the spleens of Nox1*/Y mice by day 15 p.i. However, this correlated with a decreased frequency of NP-specific CD8+ T cells in the lungs at day 15 p.i. The gene discussed is NOX1; the disease is infection.