Using single-strand conformation polymorphism analysis, Kang et al. revealed that the frameshift mutations in atg genes with mononucleotide repeats, including atg2B (mammalian atg2 homologue), atg5, atg9B (mammalian atg9 homologue), and atg12, were common in gastric cancers with high microsatellite instability (MSI) subtypes (28.1%; 9/32), while mutations were not detected in patients with low MSI [45]. The gene discussed is ATG9B; the disease is gastric cancer.