IL13 and inflammatory bowel disease: Although the contribution of the TH2 axis to IBD remains unclear (Strober et al., 2002; Shale et al., 2013), polymorphisms in IL-4, IL-5 and IL-13 have been implicated by GWAS in both CD and UC (Van Limbergen et al., 2014) and elevated levels of antibodies recognizing food and commensal antigens have been detected in IBD patients (Lodes et al., 2004; Cai et al., 2014).