While BKM120 effectively inhibited the growth of majority of the ovarian cancer cell lines examined, we failed to identify an apparent association between a particular genetic alteration (i.e. PIK3CA, K-Ras, p53, PTEN, and EGFR) [22] and cellular response to BKM120 treatment (Figure S1A and S1B). The gene discussed is TP53; the disease is ovarian cancer.