MTDH and neoplasm: Untreated control rats exhibit a median tumor volume of 383.92 mm3 ± 68.79, whereas AED-1/MTDH siRNA-1 and AED-1/MTDH siRNA-2-treated rats reveal tumor volumes of 184.27 mm3 ± 57.16, 159.47 mm3 ± 50.60 (Figure 8D).