YAP1 and neoplasm: In summary, dysregulated YAP activity has been implicated in a wide range of tumor types including intestinal stem cells, hepatocellular, pancreatic, renal, colorectal, breast, and skeletal muscle cancer (Dong et al., 2007; Tremblay et al., 2014; Patel et al., 2015) which has been further reviewed by S. Plouffe (Plouffe et al., 2015).