Infection with EBVGFPΔ130-159 virus also increased E2F1 protein, especially at 2 and 5 dpi (1.2 and 1.25 fold change respectively), but the levels were down regulated at 7 dpi (1.00 fold) consistent with the mRNA levels determined by qRT-PCR (Figure 7B). The gene discussed is E2F1; the disease is infection.