BMP4 and neoplasm: As shown in Figure 5B, mice that received s.c. injections of hGSCs, co-cultured with CM of hNSC-BMP4, showed an overall decrease in tumor volume (69.4±16.5mm3) in comparison to mice that had received an s.c. injection of hGSCs co-cultured with CM of hNSC (218.1±22.7mm3) or CM of NHAs (235.9±63.3mm3).