VEGFC and renal cell adenocarcinoma: Circulating VEGF-A and VEGF-C and sVEGFR3 have repeatedly been implicated as prognostic biomarkers across several RCC studies (Deprimo et al, 2007; Rini et al, 2008; Pena et al, 2010; Tran et al, 2012; Zurita et al, 2012).