CS and Huntington disease: In a refinement of the above-cited study [129] of protein carbonylation in the striatum of HD patients, Sorolla et al. identified 13 carbonylated, low-abundance proteins, seven of which were involved in energy production, including three glycolytic and four mitochondrial enzymes, namely, citrate synthase (CS), ubiquitous creatine kinase (CKMT1A), ubiquinol-cytochrome c reductase (complex III) core protein 2 (UQCRC2) and ATP synthase alpha subunit 1 (ATP5A1) [130].