None of the patients developed a clinical phenotype reminiscent of MOG-IgG-associated diseases such as acute disseminated encephalomyelitis (ADEM), MS, aquaporin-4-seronegative neuromyelitis optica spectrum disorder (NMOSD), isolated optic neuritis or transverse myelitis, or bilateral optic neuritis (BON) within the observation period of six months after onset of acute IM. The gene discussed is AQP4; the disease is transverse myelitis.