Third, genetic factors, especially the genes involved in obesity and lipid metabolism, such as PPAR and APOA5 genetic polymorphism [14,15,19], should be taken into consideration, because prior studies demonstrated that Europeans had higher incidence of metabolic syndrome associated with lipid metabolism [10,11,12,13,14,15,19]. This evidence concerns the gene PPARA and obesity due to melanocortin 4 receptor deficiency.