Altered expression of AQP3, AAK1, BCL2, BIRC3, BNIP3, DDX17, FOXO1, ITPR1, MYC, PRKCA, SNCA, TNFRSF25, CCR7, MS4A1 and IMPDH2 was responsible for renal necrosis, nephrosis, nephritis, proliferation and kidney failure. This evidence concerns the gene BNIP3 and kidney failure.