MCAM and cancer: Figure 6b shows that the ratios of Bax/Bcl2 were not statistically different between tumors derived from the METCAM clone 2D and those from the control (vector) clone 3D, indicating that over-expression of METCAM/MUC18 did not affect apoptosis or anti-apoptosis of SK-OV-3 cancer cells during in vivo tumorigenesis.