MCAM and melanoma: Figure 1a shows that the expression level of METCAM/MUC18 in one immortalized normal ovarian epithelial cell line (IOSE) was about 10 % and that in five ovarian cancer cell lines, BG-1, HEY, CAOV-3, SK-OV-3 and NIHOVCAR3, ranged from zero to 50 %, assuming that a positive control, human melanoma cell line SK-Mel-28, expressed 100 % of METCAM/MUC18.