MCAM and cancer: This provided an important information for us to choose two cell lines, BG-1 (established from a poorly differentiated adenocarcinoma) and SK-OV-3 (established from an adenocarcinoma metastasis as malignant ascites), which expressed very low levels of METCAM/MUC18 (zero and 1 %, respectively), for in vitro and in vivo studies.