Two healthy hiPSC lines [HUES7-fibroblast-derived FIB-hiPSC and dental pulp-derived BT1-hiPSC], and three diseased hiPSC lines (DMD-afflicted DMD4- and DMD16-hiPSCs and CPVT-afflicted CP1-hiPSCs) were generated in vitro by lentiviral delivery of the OCT4, NANOG, SOX2, and LIN28 reprogramming factors. The gene discussed is SOX2; the disease is Duchenne muscular dystrophy.