CCR5 is commonly expressed by intrathecal Th lymphocytes in both infectious (neuroborreliosis) and non-infectious (multiple sclerosis, MS) cns inflammation, usually alongside CXCR3 receptor for chemokines CXCL9 and CXCL10, but its role remains debatable [26, 28–30]. Here, CCR5 is linked to myeloid sarcoma.