CCR5 and Lyme disease: CCR5 csf expression tended to be similarly increased in a small group of patients with aseptic meningitis, while in neuroborreliosis, it was even higher: 52 % of activated Th lymphocytes was CCR5-positive, in combination with higher csf lymphocyte count resulting in 10 times higher absolute number of activated CCR5+ cells than in TBE.