Exposure of MLpvNG2+ cells to medium conditioned by cirrhotic liver homogenate derived from the livers of animals with liver cirrhosis, stimulated the generations of hepatic lineages (AFP+, Alb+, CK19+) suggesting that fate determination in these NG2-expressing hepatic progenitors can be modulated by pathologically-derived signals that may highlight their in vivo hepatic lineage differentiation potency43. The gene discussed is ALB; the disease is cirrhosis of liver.