Fig 4A shows a heatmap of 8p12 amplicon gene expression within each tumour. In accordance with the statistical analysis, FGFR1 amplified samples showed increased expression of genes across the 8p amplicon. Interestingly, in several amplified samples the relative expression of FGFR1 was lower than that of neighboring genes, suggesting the presence of additional regulators of FGFR1 expression on the background of FGFR1 amplification. This evidence concerns the gene FGFR1 and neoplasm.